Phase 1 Study of BXQ-350 in Adult Patients With Advanced Solid Tumors

PHASE1CompletedINTERVENTIONAL
Enrollment

86

Participants

Timeline

Start Date

September 1, 2016

Primary Completion Date

June 17, 2019

Study Completion Date

June 15, 2020

Conditions
Neoplasms
Interventions
DRUG

BXQ-350

BXQ-350 is a novel anti-neoplastic therapeutic agent configured from two components: Saposin C (SapC), an expressed (human) lysosomal protein, and the phospholipid dioleoylphosphatidyl-serine (DOPS), a phospholipid located on cell membranes. When both the components are assembled together stable SapC-DOPS nanovesicles are formed(clinical formulation BXQ-350).

Trial Locations (4)

40536

University of Kentucky Markey Cancer Center, Lexington

43210

The Ohio State University Comprehensive Cancer Center, Columbus

45219

University of Cincinnati Barrett Center, Cincinnati

87102

University of New Mexico Cancer Center, Albuquerque

All Listed Sponsors
collaborator

CTI Clinical Trial and Consulting Services

OTHER

lead

Bexion Pharmaceuticals, Inc.

INDUSTRY