Study to Evaluate the Effect of GBT440 in Pediatrics With Sickle Cell Disease

PHASE2TerminatedINTERVENTIONAL
Enrollment

147

Participants

Timeline

Start Date

July 5, 2016

Primary Completion Date

October 2, 2023

Study Completion Date

October 2, 2023

Conditions
Sickle Cell Disease
Interventions
DRUG

Voxelotor

"* Part A: Voxelotor will be administered as oral capsules or tablets~* Part B: Voxelotor will be administered as oral capsules or tablets~* Part C: Voxelotor will be administered as oral dispersible tablets or powder for oral suspension~* Part D: Voxelotor will be administered as oral dispersible tablets or powder for oral suspension"

Trial Locations (20)

15224

Children's Hospital of Pittsburgh of UPMC, Pittsburgh

19104

The Children's Hospital of Philadelphia, Philadelphia

20010

Children's National Medical Center, Washington D.C.

27834

Brody School of Medicine at East Carolina University, Greenville

30342

Children's Healthcare of Atlanta Scottish Rite, Atlanta

38105

St. Jude Children's Research Hospital, Memphis

44106

University Hospitals Cleveland Medical Center, Rainbow Babies & Children's Hospital, Cleveland

60611

Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago

60612

University of Illinois at Chicago Clinical Research Center, Chicago

64108

Children's Mercy Hospital, Kansas City

70809

Our Lady of the Lake Children's Hospital (IP Address), Baton Rouge

94513

Brentwood Clinic UCSF Benioff Children's Hospital Oakland, Brentwood

08903

Rutgers-Robert Wood Johnson Medical School, New Brunswick

Unknown

American University of Beirut - Medical Center, Beirut

Rafik Hariri University Hospital, Beirut

Nini Hospital, Tripoli

NW1 2PG

University College London Hospital, NHS Foundation Trust, London

E1 1BB

Barts Health NHS Trust, The Royal London Hospital, London

SE1 7EH

Guy's and St Thoma's NHS Foundation Trust, Evelina London Children's Hospital, London

M13 9WL

Manchester University NHS Foundation Trust, Royal Manchester Children's Hospital, Manchester

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Pfizer

INDUSTRY

NCT02850406 - Study to Evaluate the Effect of GBT440 in Pediatrics With Sickle Cell Disease | Biotech Hunter | Biotech Hunter