Comparison of Optimal Hypertension Regimens

PHASE4CompletedINTERVENTIONAL
Enrollment

940

Participants

Timeline

Start Date

November 30, 2016

Primary Completion Date

October 31, 2023

Study Completion Date

October 31, 2023

Conditions
Hypertension
Interventions
DRUG

Amlodipine

Amlodipine 5mg and Amlodipine 10mg will be one of the treatments in which patients will receive on the monotherapy arm and on the dual therapy arm.

DRUG

Lisinopril

"Lisinopril 10mg and Lisinopril 20mg will be one of the treatments in which patients will receive on the monotherapy arm.~Lisinopril 20mg will be one of the treatments in which patients will receive on the dual therapy arm."

DRUG

Amiloride

Amiloride 10mg will be one of the treatments in which patients will receive on the dual therapy arm.

DRUG

Chlortalidone

Chlortalidone 25mg will be one of the treatments in which patients will receive on the dual therapy arm and monotherapy arm.

Trial Locations (14)

CB2 0QQ

Cambridge University Hospitals NHS Foundation Trust, Cambridge

B15 2TH

Queen Elizabeth Hospital, Birmingham

B18 7QH

Sandwell & West Birmingham Hospitals NHS Trust, Birmingham

B9 5SS

Heartlands Hospital, Birmingham

CF64 2XX

University Hospital Llandough, Cardiff

G12 8TA

University of Glasgow, Glasgow

L14 3PE

Liverpool Heart and Chest Hospital, Liverpool

EC1M 6BQ

William Harvey Research Institute, Barts and the London Medical School, London

SE1 7EH

St Thomas' Hospital, London

SW17 0RE

St George's Hospital, London

W6 7HL

Hammersmith & Fulham GP Partnership: Richford Gate Medical Practice, London

M13 9WL

Manchester Royal Infirmary, Manchester

NG7 2UH

Nottingham University Hospital: QMC Campus, Nottingham

SG1 4AB

Lister Hospital, Stevenage

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Medical Research Council

OTHER_GOV

lead

Cambridge University Hospitals NHS Foundation Trust

OTHER

NCT02847338 - Comparison of Optimal Hypertension Regimens | Biotech Hunter | Biotech Hunter