Tenofovir Alafenamide Versus Tenofovir Disoproxil Fumarate for Treatment of Hepatitis B e Antigen-Negative Hepatitis B (China)

PHASE3CompletedINTERVENTIONAL
Enrollment

155

Participants

Timeline

Start Date

June 19, 2015

Primary Completion Date

April 5, 2017

Study Completion Date

September 18, 2023

Conditions
HBVChronic HBV Infection
Interventions
DRUG

TAF

TAF 25 mg tablet administered orally once daily

DRUG

TDF

TDF 300 mg tablet administered orally once daily

DRUG

TAF Placebo

TAF placebo tablet administered orally once daily

DRUG

TDF Placebo

TDF placebo tablet administered orally once daily

Trial Locations (29)

100015

Beijing Ditan Hospital, Beijing

100034

Peking University First Hospital, Beijing

100039

No. 302 PLA Hospital, Beijing

100044

Peking University People's Hospital, Beijing

100050

Beijing Friendship Hospital, Capital Medical University, Beijing

100069

Beijing Youan Hospital, Capital Medical University, Beijing

110004

Shengjing Hospital of China Medical University, Shenyang

110006

The sixth People's Hospital of Shenyang, Shenyang

130021

The First Hospital of Jilin University, Changchun

200025

Rui Jin Hospital Shanghai Jiao Tong University School of Medicine, Shanghai

200083

Shanghai Public Health Clinical Center, Shanghai

200235

85 Hospital of People's Liberation Army, Shanghai

210029

Jiangsu Provincial People's Hospital, Nanjing

250021

Jinan Infectious Disease Hospital, Jinan

330006

The First Affiliated Hospital of Nanchang University, Nanchang

410008

XiangYa Hospital Central South University, Changsha

410011

The 2nd Xiangya Hospital Central South University, Changsha

430030

Tongji Hospital, Tongji Medical college HuaZhong University of Science&Technology, Wuhan

510060

Guangzhou No.8 People's Hospital, Guangzhou

510515

Nanfang Medical University, Nanfang Hospital, Guangzhou

510630

The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou

530021

The 1st Affiliated Hospital of Guangxi Medical University, Nanning

550004

The Affiliated Hospital of Guiyang Medical College, Guiyang

570311

The People's Hospital of Hainan Province, Haikou

610041

West China Hospital, Sichuan University, Chengdu

650032

No.1 Hospital Affiliated to Kunming Medical College, Kunming

710061

First Affiliated Hospital of Xi'an Jiaotong, Xi'an

050051

The 3rd Hospital of Hebei Medical University, Shijiazhuang

Unknown

Nanjing No. 2 Hospital, Nanjing

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Gilead Sciences

INDUSTRY

NCT02836236 - Tenofovir Alafenamide Versus Tenofovir Disoproxil Fumarate for Treatment of Hepatitis B e Antigen-Negative Hepatitis B (China) | Biotech Hunter | Biotech Hunter