Pain Perception: Lidocaine Rate/Temp/Buffer

NAActive, not recruitingINTERVENTIONAL
Enrollment

26

Participants

Timeline

Start Date

June 30, 2016

Primary Completion Date

January 31, 2025

Study Completion Date

January 31, 2025

Conditions
Pain
Interventions
PROCEDURE

Slow, Room Temperature Injection

The room temperature local anesthetic agent will be administered by slow infiltration.

PROCEDURE

Rapid, Room Temperature Injection

The room temperature local anesthetic agent will be administered by rapid infiltration.

PROCEDURE

Slow, Warm Temperature Injection

The warmed local anesthetic agent will be administered by slow infiltration.

PROCEDURE

Rapid, Warm Temperature Injection

The warmed local anesthetic agent will be administered by rapid infiltration.

PROCEDURE

Buffered Injection

One side of the body will be randomized to receive an injection of the buffered agent, while the contralateral side will be assigned to receive an injection of the unbuffered anesthetic agent.

PROCEDURE

Non-Buffered Injection

One side of the body will be randomized to receive an injection of the buffered agent, while the contralateral side will be assigned to receive an injection of the unbuffered anesthetic agent.

DRUG

Lidocaine

Injectable lidocaine solution (Lidocaine Hydrochloride and Epinephrine)

DRUG

Buffer

Sodium Bicarbonate

Trial Locations (1)

60611

Northwestern University Department of Dermatology, Chicago

All Listed Sponsors
lead

Northwestern University

OTHER