NCT02820454View on ClinicalTrials.gov

Radiosensitization of Multiple Brain Metastases Using AGuIX Gadolinium Based Nanoparticles

PHASE1CompletedINTERVENTIONAL
Enrollment

15

Participants

Timeline

Start Date

March 31, 2016

Primary Completion Date

February 28, 2019

Study Completion Date

February 28, 2019

Conditions
Brain Metastases
Interventions
DRUG

AGuIX

A single intravenous injection on day 1. Dose level 1: 15mg/kg; Dose level 2: 30mg/kg, Dose level 3: 50mg/kg; Dose level 4: 75mg/kg; Dose level 5: 100mg/kg

RADIATION

whole brain radiation therapy

30Gy in 10 sessions of 3Gy (5 days a week in weeks 1-2); first session 4 hours after AGuIX injection.

Trial Locations (1)

38100

University Hospital Grenoble, Grenoble

Sponsors

Collaborators (1)

NH TherAguix SAS
All Listed Sponsors
collaborator

NH TherAguix SAS

OTHER

lead

University Hospital, Grenoble

OTHER