Study of Oral Azacitidine (CC-486) in Combination With Pembrolizumab (MK-3475) in Patients With Metastatic Melanoma

PHASE2Active, not recruitingINTERVENTIONAL
Enrollment

24

Participants

Timeline

Start Date

February 14, 2017

Primary Completion Date

February 28, 2026

Study Completion Date

February 28, 2026

Conditions
Melanoma and Other Malignant Neoplasms of SkinMetastatic Melanoma
Interventions
DRUG

Azacitidine

300 mg by mouth daily for 15 days (Days 1-15) of every cycle.

DRUG

Pembrolizumab

200 mg by vein every 3 weeks and after the oral dose of Azacitidine on concurrent treatment days.

Trial Locations (1)

77330

University of Texas MD Anderson Cancer Center, Houston

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Merck Sharp & Dohme LLC

INDUSTRY

collaborator

Celgene

INDUSTRY

lead

M.D. Anderson Cancer Center

OTHER