Comparative Effectiveness of Pulmonary Embolism Prevention After Hip and Knee Replacement

PHASE4Active, not recruitingINTERVENTIONAL
Enrollment

20,000

Participants

Timeline

Start Date

December 31, 2016

Primary Completion Date

July 31, 2025

Study Completion Date

July 31, 2025

Conditions
Pulmonary EmbolismVenous Thrombosis
Interventions
DRUG

Enteric Coated Aspirin

DRUG

Warfarin

DRUG

Rivaroxaban

Trial Locations (32)

10016

New York University, New York

10075

Northwell Health, New York

17033

Penn State Hershey Med Center, Hershey

19104

University of Pennsylvania, Philadelphia

21215

Sinai Hospital, Baltimore

21218

Johns Hopkins University, Baltimore

22306

Anderson Orthopaedic Institute (VA), Alexandria

22908

University of Virginia, Charlottesville

23284

Virginia Commonwealth University Medical Center, Richmond

26506

West Virginia University, Morgantown

27710

Duke University Medical Center, Durham

29425

Medical University of South Carolina, Charleston

33143

Arthritis Surgery Research Foundation, South Miami

44195

Cleveland Clinic, Cleveland

46037

Indiana University, Indianapolis

55905

Mayo Clinic, Rochester

60612

Rush University Medical Center, Chicago

68198

University of Nebraska Medical Center, Omaha

72205

University of Arkansas for Medical Sciences, Little Rock

84132

University of Utah, Salt Lake City

85259

Mayo Clinic, Scottsdale

90404

UCLA, Los Angeles

94305

Stanford University Hospital, Stanford

98133

University of Washington, Seattle

02115

Brigham & Women's Hospital, Boston

02118

Boston University Medical Center, Boston

02215

Beth Israel Deaconess Medical Center, Boston

01805

Lahey Clinic, Burlington

03756

Dartmouth-Hitchcock Medical Center, Lebanon

02914

Lifespan Health, East Providence

N6A 4V2

London Health Sciences Centre, London

K1H 8L6

University of Ottawa, Ottawa

All Listed Sponsors
collaborator

Patient-Centered Outcomes Research Institute

OTHER

collaborator

University of Maryland, Baltimore

OTHER

collaborator

Brigham and Women's Hospital

OTHER

collaborator

Northwestern University

OTHER

collaborator

Medical University of South Carolina

OTHER

lead

Dartmouth-Hitchcock Medical Center

OTHER