Clinical Trial of Chidamide Combined With CHOP in Peripheral T-cell Lymphoma Patients

In the lead-in period, patients take a single dose of Chidamide tablet on the first day and then off for 3 days before the first cycle begins. In the subsequent treatment cycles, Chidamide tablets are given orally on Day 1,4,8 and 11 of each cycle.

On Day 1, cyclophosphamide is given in a 20-minute intravenous (IV) infusion at 750 mg/m\^2 in 5 minutes after chidamide administration

On Day 1, Adriacin is given in a 20-minute IV infusion at 50 mg/m\^2 soon after cyclophosphamide administration.

On Day 1, vincristine is given in IV infusion at 1.4 mg/m\^2 after adriacin administration.

On Day 1 to 5, prednisone is given orally at 100 mg once a day