NCT02807051 - To Evaluate the Effect of Clarithromycin on the Systemic Exposure of Pacritinib in Healthy Subjects | Biotech Hunter

Enrollment

Participants

Timeline

Start Date

September 30, 2014

Primary Completion Date

October 31, 2014

Study Completion Date

October 31, 2014

Conditions

Drug Interaction Study

Interventions

DRUG

Pacritinib

Single 400-mg dose (four 100-mg capsules) administered in the morning on Days 1 and 12

DRUG

Clarithromycin

Twice-daily, 500-mg dose (one 500-mg tablet) administered every 8 to 12 hours on Day 8 through the morning of Day 12

DRUG

Pacritinib and Clarithromycin

On Day 12, a single oral 400-mg dose of pacritinib was co-administered with the final 500-mg dose of clarithromycin

Trial Locations (1)

Covance Clinical Research Unit, Daytona Beach