Immune Profile in Subjects With New Onset Type 1 Diabetes

Inguinal lymph node will be localized by ultrasonography and sampled by 21-gauge needle and a 5 mL syringe using to and fro needle movement while applying 1 mL suction with the syringe. Up to 2 fine needle aspirate passages will be obtained, to derive immune cells.

Inguinal lymph node will be localized by ultrasonography and following fine needle aspirate, an incision will be made. Up to five core biopsies will be obtained, to derive immune cells.

Blood sample (30 mL) will be collected, to derive immune cells.

All subjects will be asked to complete a questionnaire about their expectations/experiences of undergoing the biopsy procedures.