Single and Repeated Dose Escalation Study of GSK2838232

PHASE1CompletedINTERVENTIONAL
Enrollment

62

Participants

Timeline

Start Date

March 31, 2016

Primary Completion Date

December 31, 2016

Study Completion Date

December 31, 2016

Conditions
Infection, Human Immunodeficiency Virus
Interventions
DRUG

GSK2838232 PIB

GSK2838232 will be available as oral suspension for reconstitution, will be administered as 50, 100 and 200 mg in Part A and as 20, 50, 100 or 200 mg in Part B.

DRUG

GSK2838232 IR1

GSK2838232 will be available as film-coated tablet for oral use

DRUG

GSK2838232 IR2

GSK2838232 will be available as film-coated tablet for oral use

DRUG

Placebo PIB

Oral suspension of hydromellulose acetate succinate will be supplied as powder-in-bottle for reconstitution.

DRUG

Ritonavir

It is to be purchased by site. It will be white film-coated ovaloid tablets for oral administration.

Trial Locations (1)

21225

GSK Investigational Site, Baltimore

Sponsors

Lead Sponsor

All Listed Sponsors
lead

GlaxoSmithKline

INDUSTRY