A Phase 2a Study to Evaluate the Effects of Sirukumab in Subjects With Severe Poorly Controlled Asthma

PHASE2WithdrawnINTERVENTIONAL
0
Timeline

Start Date

September 23, 2016

Primary Completion Date

October 4, 2016

Study Completion Date

October 4, 2016

Conditions
Asthma
Interventions
DRUG

Sirukumab

This intervention will be provided in a 1.0 mL pre-filled syringe (PFS) fitted with spring-powered, disposable autoinjector device for single SC use that is permanently assembled on the syringe. The sirukumab PFS is aseptically filled to deliver a dose of 50 mg/1.0 mL of sirukumab.

DRUG

Placebo

This intervention will be provided in a 1.0 mL pre-filled syringe (PFS) fitted with spring-powered, disposable autoinjector device for single SC use that is permanently assembled on the syringe. The sirukumab PFS is aseptically filled to deliver a dose of 50 mg/1.0 mL of sirukumab.

DRUG

Rescue medication

Rescue medication (salbutamol/albuterol) shall be supplied to subjects at Screening for use when needed during the study.

Trial Locations (8)

15706

GSK Investigational Site, Santiago de Compostela. La Coruña.

17005

GSK Investigational Site, Girona

23225

GSK Investigational Site, Richmond

23229

GSK Investigational Site, Richmond

28922

GSK Investigational Site, Alcorcón (Madrid)

33180

GSK Investigational Site, Aventura

45231

GSK Investigational Site, Cincinnati

90808

GSK Investigational Site, Long Beach

Sponsors

Lead Sponsor

All Listed Sponsors
lead

GlaxoSmithKline

INDUSTRY