Acthar SLE (Systemic Lupus Erythematosus)

PHASE4WithdrawnINTERVENTIONAL
0
Timeline

Start Date

October 31, 2016

Primary Completion Date

May 22, 2019

Study Completion Date

May 22, 2019

Conditions
Systemic Lupus Erythematosus (SLE)Repository Corticotropin Injection
Interventions
DRUG

Acthar low dose (40 U)

The 40U group will administer 0.5 mL of study medication once a day. Patients will taper study medication during Week 2 through the remainder of the study and will administer 0.5 mL of study medication twice a week. The stable Acthar regimen should be maintained for the remainder of the study. However, dose adjustments may be implemented if needed based on safety.

DRUG

Acthar high dose (80 U)

The 80U group will administer 1.0 mL of study medication every day. If a patient meets dose reduction criteria, their assigned volume will be adjusted from 1.0 mL to 0.5 mL. Patients will taper study medication during Week 2 through the remainder of the study. However, dose adjustments may be implemented if needed based on safety.

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Mallinckrodt

INDUSTRY

lead

NYU Langone Health

OTHER