30
Participants
Start Date
August 31, 2012
Primary Completion Date
June 30, 2015
Study Completion Date
June 30, 2015
Pioglitazone
Subjects randomized to pioglitazone begin with a starting dose of 15 mg daily administered. The dose will be titrated up to 30mg on the second week and 45 mg on the third week of the study. Subjects will remain on 45 mg of pioglitazone until the end of week 12. At the end of week 12 the study medication will be discontinued.
Placebo
Subjects randomized to placebo receive placebo capsules once daily across all twelve weeks of the study.
Therapy
Cognitive-behavioral therapy 1 hour per week
Contingency Management
Prize-based contingency management for attendance
The University of Texas Health Science Center at Houston, Houston
National Institute on Drug Abuse (NIDA)
NIH
The University of Texas Health Science Center, Houston
OTHER