Study CB-839 in Combination With Nivolumab in Patients With Melanoma, Clear Cell Renal Cell Carcinoma (ccRCC) and Non-Small Cell Lung Cancer (NSCLC)

PHASE1/PHASE2TerminatedINTERVENTIONAL
Enrollment

118

Participants

Timeline

Start Date

August 1, 2016

Primary Completion Date

April 24, 2020

Study Completion Date

April 24, 2020

Conditions
Clear Cell Renal Cell Carcinoma (ccRCC)MelanomaNon-small Cell Lung Cancer (NSCLC)
Interventions
DRUG

CB-839

Glutaminase inhibitor

DRUG

Nivolumab

PD-1 inhibitor

Trial Locations (17)

10016

New York University, New York

10032

Columbia University Medical Center, New York

10655

Memorial Sloan Kettering Cancer Center, New York

19104

University of Pennsylvania, Philadelphia

30607

University Cancer Blood Center, Athens

37232

Vanderbilt University, Nashville

44106

University Hospitals Cleveland, Cleveland

48201

Karmanos Caner Center, Detroit

77030

University of Texas MD Anderson Cancer Center, Houston

80045

University of Colorado, Aurora

85016

Honor Health, Scottsdale

94304

Stanford University, Palo Alto

98109

Seattle Cancer Care Alliance/University of Washington, Seattle

98405

Northwest Medical Specialties, Tacoma

02114

Beth Israel Deaconess Medical Center, Boston

Massachusetts General Hospital, Boston

02215

Dana-Farber Cancer Institute, Boston

Sponsors
All Listed Sponsors
lead

Calithera Biosciences, Inc

INDUSTRY

NCT02771626 - Study CB-839 in Combination With Nivolumab in Patients With Melanoma, Clear Cell Renal Cell Carcinoma (ccRCC) and Non-Small Cell Lung Cancer (NSCLC) | Biotech Hunter | Biotech Hunter