Study To Confirm Efficacy and Safety of Terlipressin in Hepatorenal Syndrome (HRS) Type 1

PHASE3CompletedINTERVENTIONAL
Enrollment

300

Participants

Timeline

Start Date

July 13, 2016

Primary Completion Date

July 24, 2019

Study Completion Date

July 24, 2019

Conditions
Hepatorenal Syndrome
Interventions
DRUG

Terlipressin

Terlipressin solution for injection

OTHER

Placebo

Matching placebo solution for injection

Trial Locations (64)

10016

NYU Langone Health, New York

10021

Weil Cornell Medical College, New York

10029

Mount Sinai Medical Center, New York

10467

Montefiore Medical Center, The Bronx

15240

VA Pittsburgh Healthcare System, Pittsburgh

19102

Drexel University, Philadelphia

19104

Hospital of the University of Pennsylvania, Philadelphia

19107

Jefferson University, Philadelphia

20007

MedStar Georgetown University Hospital, Washington D.C.

21202

Mercy Medical Center, Baltimore

22908

University of Virginia Medical Center, Charlottesville

23245

McGuire VA Medical Center, Richmond

23298

Virginia Commonwealth University, Richmond

29425

Medical University of South Carolina, Charleston

30309

Piedmont Hospital Transplant, Atlanta

30329

Emory University Hospital, Atlanta

32224

Mayo Clinic - FL, Jacksonville

32610

University of Florida, Gainesville

33136

Jackson Memorial Hospital, Miami

University of Miami, Miami

33606

Tampa General Medical Group, Tampa

35294

University of Alabama at Birmingham, Birmingham

37232

Vanderbilt University Medical Center, Nashville

43210

The Ohio State University Wexner Medical Center, Columbus

44106

Case Western Reserve Transplant, Cleveland

48109

University of Michigan Medical Center, Ann Arbor

52242

University of Iowa Hospitals & Clinics, Iowa City

55455

University of Minnesota, Minneapolis

55902

Mayo Clinic - MN, Rochester

60611

Northwestern University, Chicago

60612

Rush University Medical Center, Chicago

63110

Saint Louis University, St Louis

Washington University in St. Louis, St Louis

66160

University of Kansas Medical Center, Kansas City

68198

University of Nebraska Medical Center, Omaha

70121

Ochsner Clinic Foundation, New Orleans

73112

INTEGRIS Baptist Medical Center, Oklahoma City

75235

Parkland Health and Hospital System, Dallas

75246

Baylor University Medical Center, Dallas

75390

UT Southwestern Medical Center, Dallas

76104

Baylor Scott and White All Saints Medical Center, Fort Worth

77030

Baylor College of Medicine (St. Luke's), Houston

Methodist Center for Liver Disease and Transplantation, Houston

78229

Methodist Transplant Hospital, San Antonio

University of Texas Health Science Center at San Antonio, San Antonio

84132

University of Utah, Salt Lake City

85006

Banner Good Samaritan Medical Center, Phoenix

85057

Mayo Clinic - AZ, Phoenix

85724

University of Arizona, Tucson

90033

USC Healthcare, Los Angeles

90095

UCLA Medical Center, San Diego

92118

Southern California Research Center, San Diego

94115

California Pacific Medical Center, San Francisco

94305

Stanford Hospital and Clinics, Palo Alto

98104

Harborview Medical Center/Univ. of Washington, Seattle

Swedish Organ Transplant and Liver Center, Seattle

98105

University of Washington, Seattle

02215

Beth Israel Deaconess Medical Center, Boston

07102

Rutgers New Jersey Medical School, Newark

V5Z IM9

Vancouver General Hospital, Gordon and Leslie Diamond Health Care Centre, Vancouver

K1H 8L6

Ottawa Hospital, Ottawa

M5G2C4

University of Toronto 9N/983 Toronto General Hospital, Toronto

H4A3J1

McGill University Health Centre, Montreal

H2X3J4

Centre Hospitalier de l'Université de Montréal, Québec

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Mallinckrodt

INDUSTRY