MRI of Glymphatic Clearance During Anesthetic Sedation

EARLY_PHASE1CompletedINTERVENTIONAL
Enrollment

17

Participants

Timeline

Start Date

July 31, 2014

Primary Completion Date

February 9, 2017

Study Completion Date

December 31, 2017

Conditions
Glymphatic Flow
Interventions
OTHER

Brain connectivity and physiology

MRI to measure glymphactic flow during simulated natural sleep and again on return to wakefulness.

DRUG

Dexmedetomidine

Administering of 0.5-1.0 mcg/kg/hr of dexmedetomidine to ensure subject's loss of consciousness.

Trial Locations (1)

19104

University of Pennsylvania, Philadelphia

All Listed Sponsors
lead

University of Pennsylvania

OTHER

NCT02768688 - MRI of Glymphatic Clearance During Anesthetic Sedation | Biotech Hunter | Biotech Hunter