Comparative Study Between Hydrocortisone and Mannitol in Treatment of Postdural Puncture Headache

PHASE4CompletedINTERVENTIONAL
Enrollment

50

Participants

Timeline

Start Date

October 31, 2014

Primary Completion Date

November 30, 2015

Study Completion Date

November 30, 2015

Conditions
Headache
Interventions
DRUG

hydrocortisone 100mg.

Group (I), received hydrocortisone 100mg, dissolved in 2ml normal saline, intravenously/8 hours for 48 hours

DRUG

mannitol 20% intravenous fluid

group (II), received mannitol 20% 100ml intravenously which was given over 30 minutes and followed by 100 ml on a 12hour basis. Urinary catheter was inserted for patients in group (II) under complete aseptic conditions by the anesthesia resident before the start of mannitol infusion and removed after its discontinuation, accompanied by the intravenous fluid infusion over 48 hours of 500ml of normal saline or Ringer's solution every 8 hours and the input/output fluid chart for evaluation of fluid balance.

All Listed Sponsors
lead

Ain Shams University

OTHER

NCT02760862 - Comparative Study Between Hydrocortisone and Mannitol in Treatment of Postdural Puncture Headache | Biotech Hunter | Biotech Hunter