Gene Therapy for X-linked Chronic Granulomatous Disease

PHASE1/PHASE2Active, not recruitingINTERVENTIONAL
Enrollment

3

Participants

Timeline

Start Date

March 31, 2016

Primary Completion Date

June 30, 2034

Study Completion Date

June 30, 2034

Conditions
X-Linked Chronic Granulomatous Disease
Interventions
GENETIC

X vivo gene therapy

Transplantation of patient's autologous CD34+ cells transduced with lentiviral vector containing XCGD gene. The investigational product is patient-specific and corresponds to autologous CD34+ cells transduced ex vivo with the G1XCGD vector. These transduced cells will be cryopreserved until safety testing and infusion into the patient.

Trial Locations (1)

75015

Hôpital Necker Enfants Malades, Paris

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Genethon

OTHER

NCT02757911 - Gene Therapy for X-linked Chronic Granulomatous Disease | Biotech Hunter | Biotech Hunter