Ascending Dose Study of the Safety of AB-SA01 When Topically Applied to Intact Skin of Healthy Adults

PHASE1CompletedINTERVENTIONAL
Enrollment

12

Participants

Timeline

Start Date

May 31, 2016

Primary Completion Date

August 31, 2016

Study Completion Date

August 31, 2016

Conditions
Healthy Volunteers
Interventions
BIOLOGICAL

AB-SA01 (10^8 PFU per phage)

Gauze pads will be saturated with AB-SA01 and then applied to each subject's volar forearm and covered with occlusive dressing once daily for 3 consecutive days. Placement of the gauze to each subject's right or left volar forearm will be randomized and double-blinded.

BIOLOGICAL

AB-SA01 (10^9 PFU per phage)

Gauze pads will be saturated with AB-SA01 and then applied to each subject's volar forearm and covered with occlusive dressing once daily for 3 consecutive days. Placement of the gauze to each subject's right or left volar forearm will be randomized and double-blinded.

BIOLOGICAL

Placebo (for Cohort 10^8)

Gauze pads will be saturated with Placebo and then applied to each subject's volar forearm and covered with occlusive dressing once daily for 3 consecutive days. Placement of the gauze to each subject's right or left volar forearm will be randomized and double-blinded.

BIOLOGICAL

Placebo (for Cohort 10^9)

Gauze pads will be saturated with Placebo and then applied to each subject's volar forearm and covered with occlusive dressing once daily for 3 consecutive days. Placement of the gauze to each subject's right or left volar forearm will be randomized and double-blinded.

Trial Locations (1)

20910

Clinical Trials Center, WRAIR, Silver Spring

Sponsors
All Listed Sponsors
collaborator

Walter Reed Army Institute of Research (WRAIR)

FED

lead

Armata Pharmaceuticals, Inc.

INDUSTRY

NCT02757755 - Ascending Dose Study of the Safety of AB-SA01 When Topically Applied to Intact Skin of Healthy Adults | Biotech Hunter | Biotech Hunter