340,000
Participants
Start Date
December 5, 2015
Primary Completion Date
December 31, 2024
Study Completion Date
December 31, 2025
Water, sanitation, and hygiene (WASH) intervention
WASH arm: Communities will receive the water, sanitation, and hygiene (WASH) intervention including water point construction and maintenance, hygiene and sanitation education and promotion, community-based hygiene promotion workers, household wash stations, household WASH education books, household soap distribution, and a hygiene curriculum for primary schools.
Standard of care WASH intervention
Stand of care WASH arm
Azithromycin
20mg/kg
Tetracycline
Tetracycline will be administered in lieu of azithromycin if individual is under 6 months, has a known azithromycin allergy, or is severely ill.
Control
The control group will receive no intervention during the trial. They will be enrolled in mass antibiotic treatment at the conclusion of the trial.
The Carter Center Ethiopia, Addis Ababa
The Carter Center
OTHER
Amhara Public Health Institute
UNKNOWN
Emory University
OTHER
National Eye Institute (NEI)
NIH
University of California, San Francisco
OTHER