Sanitation, Water, and Instruction in Face-washing for Trachoma I/II

PHASE3Active, not recruitingINTERVENTIONAL
Enrollment

340,000

Participants

Timeline

Start Date

December 5, 2015

Primary Completion Date

December 31, 2024

Study Completion Date

December 31, 2025

Conditions
Trachoma
Interventions
BEHAVIORAL

Water, sanitation, and hygiene (WASH) intervention

WASH arm: Communities will receive the water, sanitation, and hygiene (WASH) intervention including water point construction and maintenance, hygiene and sanitation education and promotion, community-based hygiene promotion workers, household wash stations, household WASH education books, household soap distribution, and a hygiene curriculum for primary schools.

BEHAVIORAL

Standard of care WASH intervention

Stand of care WASH arm

DRUG

Azithromycin

20mg/kg

DRUG

Tetracycline

Tetracycline will be administered in lieu of azithromycin if individual is under 6 months, has a known azithromycin allergy, or is severely ill.

OTHER

Control

The control group will receive no intervention during the trial. They will be enrolled in mass antibiotic treatment at the conclusion of the trial.

Trial Locations (1)

Unknown

The Carter Center Ethiopia, Addis Ababa

All Listed Sponsors
collaborator

The Carter Center

OTHER

collaborator

Amhara Public Health Institute

UNKNOWN

collaborator

Emory University

OTHER

collaborator

National Eye Institute (NEI)

NIH

lead

University of California, San Francisco

OTHER