An Evaluation AZD2014 Alone and in Combination With Rituximab in Relapsed/Refractory Diffuse Large B Cell Lymphoma

PHASE2CompletedINTERVENTIONAL
Enrollment

36

Participants

Timeline

Start Date

October 31, 2015

Primary Completion Date

September 7, 2017

Study Completion Date

February 6, 2020

Conditions
Diffuse Large B-Cell Lymphoma
Interventions
DRUG

AZD 2014

AZD2014 125mg BD - 2 days on 5 days off in a 28 day cycle

DRUG

Rituximab

Rituximab 375mg/m2 will be administered intravenously on day 1 of a 28 day cycle for a total of 6 cycles.

Trial Locations (9)

Unknown

Aberdeen Royal Infirmary, Aberdeen

L7 8XP

Royal Liverpool University Hospital, Liverpool

NW1 2PG

University College London Hospitals, London

SE1 9RT

Guys Hospital, London

M20 4BX

The Christie NHS Foundation Trust, Manchester

NR4 7UY

Norfolk & Norwich University Hospitals NHS Foundation Trust, Norwich

OX3 7LE

The Churchill Hospital, Oxford

PL6 8DH

Derriford Hospital, Plymouth

S016 6YD

University Hospital Southampton NHS Foundation Trust, Southampton

Sponsors
All Listed Sponsors
collaborator

Bloodwise

OTHER

collaborator

AstraZeneca

INDUSTRY

collaborator

Cancer Research UK

OTHER

lead

University of Birmingham

OTHER