Impact of Probiotics on Urinary Symptoms in Spinal Cord Injury SCI and SB

PHASE2CompletedINTERVENTIONAL
Enrollment

96

Participants

Timeline

Start Date

January 31, 2016

Primary Completion Date

October 31, 2018

Study Completion Date

October 31, 2018

Conditions
Lower Urinary Tract Symptoms
Interventions
DRUG

Lactobacillus rhamnosus GG

For the intravesicular Lactobacillus instillation, participants will be instructed to mix the contents of 1 Lactobacillus capsule into 45 cc sterile 0.9% saline.5,6 After mixing, participants will draw up the 45 cc of the liquid Lactobacillus mixture into a 60cc catheter tip syringe and instill via the intermittent catheter after the last catheterization prior to going to bed. Participants will receive 10 Lactobacillus GG tabs at the beginning of treatment phase. At the end of each month, the coordinator or RA will ask how many remaining tablets the participant has, and if needed dispense the next supply of 10 tablets Participants will be instructed to complete the USQ-NB weekly.

Trial Locations (2)

20010

Children's National Medical Center, Washington D.C.

MedStar National Rehabilitation Hospital, Washington D.C.

All Listed Sponsors
collaborator

Patient-Centered Outcomes Research Institute

OTHER

collaborator

Georgetown University

OTHER

collaborator

Children's National Research Institute

OTHER

lead

Medstar Health Research Institute

OTHER