225
Participants
Start Date
February 28, 2002
Primary Completion Date
March 31, 2006
Study Completion Date
January 31, 2008
Xeloda
Participants will receive oral Xeloda, 950 mg/m\^2 twice a day on Days 1 to 14 of each 21-day cycle.
Taxotere
Participants will receive Taxotere, 75 milligrams per meter-squared (mg/m\^2) in the Herceptin + Taxotere + Xeloda arm or 100 mg/m\^2 in the Herceptin + Taxotere arm, via IV infusion on Day 1 of each 21-day cycle. The lower starting dose will be used in the triple-therapy arm.
Herceptin
Participants will receive Herceptin, 6 milligrams per kilogram (mg/kg) via IV infusion, on Day 1 of each 21-day cycle. The first dose will be a loading dose of 8 mg/kg in Cycle 1; the dose of 6 mg/kg will be given from Cycle 2 onward.
Panama City
Camperdown
Melbourne
Melbourne
Geelong
Brisbane
Southport
Adelaide
Perth
San José
Athens
Marseille
Distrito Federal
Rozzano
Turku
Treviglio
Besançon
Lleida
Pátrai
Noale
Rennes
Legnago
Grenoble
Trento
Zaragoza
Monterrey
Monterrey
Karlstad
Pierre-Bénite
Heraklion
Västerås
Paris
Mérida
Porto Alegre
Rio de Janeiro
São Paulo
Calgary
Ottawa
Québec
Guatemala City
Gdansk
Szczecin
Barcelona
Sabadell, Barcelona
Ipswich
Leeds
Manchester
Northwood
Oxford
Southampton
Weston-super-Mare
Hoffmann-La Roche
INDUSTRY