NCT02743910View on ClinicalTrials.gov

Monitoring Plasma Tumor DNA in Early-Stage Breast Cancer

Active, not recruitingOBSERVATIONAL
Enrollment

229

Participants

Timeline

Start Date

July 31, 2016

Primary Completion Date

February 28, 2019

Study Completion Date

July 31, 2026

Conditions
Breast Cancer
Interventions
OTHER

ptDNA

Pre-operative blood samples for ptDNA will be collected at the time of diagnosis/prior to NAT, post-cycle 1/pre-cycle 2 of NAT, after all NAT/immediately before surgery, and post-operatively at 6, 12, 24, and 36 months, and annually thereafter if funding allows.

OTHER

Tissue sample

Representative tissue sample will be collected from the diagnostic biopsy (in all participants) and definitive surgery (if available)

Trial Locations (1)

21287

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore

All Listed Sponsors
collaborator

Translational Breast Cancer Research Consortium

OTHER

lead

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

OTHER

NCT02743910 - Monitoring Plasma Tumor DNA in Early-Stage Breast Cancer | Biotech Hunter | Biotech Hunter