Neoadjuvant Combination Biotherapy With Ipilimumab and Nivolumab or Nivolumab Alone

PHASE1/PHASE2WithdrawnINTERVENTIONAL
0
Timeline

Start Date

October 31, 2016

Primary Completion Date

February 9, 2017

Study Completion Date

February 9, 2017

Conditions
Melanoma
Interventions
DRUG

Nivolumab - Arm A

Nivolumab will be given during the induction phase of the study for 6 weeks. This is followed by surgery. Then maintenance therapy (after recovery from surgery).

DRUG

Nivolumab + Ipilimumab - Arm B

Nivolumab + ipilimumab during the induction phase of the study for 6 weeks. This is followed by surgery (week 6-8+). Then maintenance therapy will be initiated for up to one year from study drug initial administration ((after recovery from surgery).

Trial Locations (1)

15232

UPMC Cancer Center Hillman Cancer Center, Pittsburgh

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Bristol-Myers Squibb

INDUSTRY

lead

University of Pittsburgh

OTHER