Phase I/Ib Trial of LSZ102 Single Agent or LSZ102 + LEE011 or LSZ102 + BYL719 in ER+ Breast Cancers

PHASE1TerminatedINTERVENTIONAL
Enrollment

199

Participants

Timeline

Start Date

June 14, 2016

Primary Completion Date

September 13, 2021

Study Completion Date

September 13, 2021

Conditions
Advanced or Metastatic ER+ Breast Cancer
Interventions
DRUG

LSZ102

LSZ102

DRUG

LEE011

LEE011

DRUG

BYL719

BYL719

Trial Locations (10)

1200

Novartis Investigative Site, Brussels

10065

Memorial Sloan Kettering Cancer Center, New York

20133

Novartis Investigative Site, Milan

20141

Novartis Investigative Site, Milan

69373

Novartis Investigative Site, Lyon

77030

MD Anderson Cancer Center SC - LSZ102X2101, Houston

89081

Novartis Investigative Site, Ulm

169610

Novartis Investigative Site, Singapore

02114

Massachusetts General Hospital Massachusetts General Hospital, Boston

135 8550

Novartis Investigative Site, Koto Ku

Sponsors
All Listed Sponsors
lead

Novartis Pharmaceuticals

INDUSTRY