4,570
Participants
Start Date
December 19, 2016
Primary Completion Date
May 14, 2020
Study Completion Date
March 31, 2025
Cabotegravir Oral Tablet
30 mg tablet
TDF/FTC tablets
300 mg/200 mg fixed-dose combination tablets
Placebo for TDF/FTC tablets
Placebo for cabotegravir oral tablet
CAB LA
Administered as one 3 mL (600 mg) IM injection in the gluteal muscle at two time points 4 weeks apart and every 8 weeks thereafter
Placebo for CAB LA
Administered as one 3 mL IM injection in the gluteal muscle at two time points 4 weeks apart and every 8 weeks thereafter
ACSA CRS, Iquitos
Groote Schuur HIV CRS, Cape Town
Weill Cornell Chelsea CRS, New York
Harlem Prevention Center CRS, New York
New York Blood Center CRS, New York
Thai Red Cross AIDS Research Centre (TRC-ARC) CRS, Pathum Wan
Bronx Prevention Research Center CRS, The Bronx
Silom Community Clinic CRS, Bangkok
Via Libre CRS, Lima
Barranco CRS, Lima
CITBM - UNIDEC, Centro de Investigaciones Tecnológicas, Biomédicas y Medioambientales CRS, Bellavista
Penn Prevention CRS, Philadelphia
Johns Hopkins University CRS, Baltimore
Greensboro CRS, Greensboro
Chapel Hill CRS, Chapel Hill
The Hope Clinic of the Emory Vaccine Center CRS, Decatur
Alabama CRS, Birmingham
Ohio State University CRS, Columbus
Cincinnati Clinical Research Site, Cincinnati
CMU HIV Prevention CRS, Chiang Mai
Adolescent & Young Adult Research at The CORE Center (AYAR at CORE), Chicago
UIC Project WISH CRS, Chicago
New Orleans Adolescent Trials Unit CRS, New Orleans
Houston AIDS Research Team CRS, Houston
Children's Hospital Colorado CRS, Aurora
UCLA Vine Street Clinic CRS, Los Angeles
UCLA CARE Center CRS, Los Angeles
Bridge HIV CRS, San Francisco
East Bay AIDS Center (EBAC) CRS, Oakland
Yen Hoa Health Clinic CRS, Hanoi
George Washington Univ. CRS, Washington D.C.
The Ponce de Leon Center CRS, Atlanta
Fenway Health (FH) CRS, Boston
Washington University Therapeutics (WT) CRS, St Louis
New Jersey Medical School Clinical Research Center CRS, Newark
St. Jude Children's Research Hospital CRS, Memphis
Hospital General de Agudos JM Ramos Mejía CRS, Ciudad de Buenos Aires
Fundacion Huesped CRS, Buenos Aires
Hospital Nossa Senhora da Conceicao CRS, Porto Alegre
Centro de Referencia e Treinamento DST/AIDS CRS, São Paulo
Instituto de Pesquisa Clinica Evandro Chagas (IPEC) CRS, Rio de Janeiro
Centro de Pesquisas Clínicas IC-HCFMUSP CRS, São Paulo
San Miguel CRS, Lima
Collaborators (2)
ViiV Healthcare
INDUSTRY
Gilead Sciences
INDUSTRY
National Institute of Allergy and Infectious Diseases (NIAID)
NIH