A Pragmatic Trial of Corticosteroid Optimisation in Severe Asthma

NACompletedINTERVENTIONAL
Enrollment

300

Participants

Timeline

Start Date

January 1, 2016

Primary Completion Date

June 19, 2019

Study Completion Date

June 19, 2019

Conditions
Severe Persistent Asthma
Interventions
OTHER

Biomarker based adjustment of corticosteroid dose

The subject's corticosteroid dose will be adjusted based upon biomarker results (FeNO, eosinophils and periostin)

Trial Locations (11)

BT9 7AB

Belfast Health and Social Care Trust, Belfast

Unknown

Heart of England NHS Foundation Trust, Birmingham

NHS Greater Glasgow and Clyde, Glasgow

University Hospitals of Leicester NHS Trust, Leicester

Royal Brompton & Harefield NHS Foundation Hospital, London

University College London Hospitals NHS Foundation, London

University Hospitals of South Manchester NHS Trust, Manchester

Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne

Nottingham University Hospitals NHS Foundation Trust, Nottingham

Oxford University Hospitals NHS Trust, Oxford

University Hospital of Southampton NHS Foundation Trust, Southampton

Sponsors
All Listed Sponsors
collaborator

Medical Research Council

OTHER_GOV

collaborator

Hoffmann-La Roche

INDUSTRY

collaborator

Aerocrine AB

INDUSTRY

lead

Belfast Health and Social Care Trust

OTHER