Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of IONIS ANGPTL3-LRx in Healthy Volunteers With Elevated Triglycerides and Participants With Familial Hypercholesterolemia

PHASE1CompletedINTERVENTIONAL

Enrollment

Participants

Timeline

Start Date

November 30, 2015

Primary Completion Date

April 12, 2017

Study Completion Date

June 26, 2017

Conditions

HypertriglyceridemiaFamilial Hypercholesterolemia

Interventions

DRUG

IONIS ANGPTL3-LRx

DRUG

Placebo

0.9%NaCl, water, riboflavin

Trial Locations (1)

Clinical Site, Toronto