784
Participants
Start Date
May 31, 2016
Primary Completion Date
July 2, 2019
Study Completion Date
July 30, 2019
Vortioxetine 10 mg/day
10 mg/day, encapsulated tablet (with addition of lower initial dose levels). Based on tolerability the dose may be reduced by 5 mg/day. No dose increase will be allowed
Vortioxetine 20 mg/day
20 mg/day, encapsulated tablet (with addition of lower initial dose levels). Based on tolerability the dose may be reduced by 5 mg/day. No dose increase will be allowed
Fluoxetine 20 mg/day
20 mg/day, encapsulated tablet (with addition of lower initial dose levels). Based on tolerability the dose may be reduced by 10 mg/day. No dose increase will be allowed
Placebo
Encapsulated tablet
US1369, Dothan
US1333, Tucson
US1310, Little Rock
US1062, Costa Mesa
US1387, Downey
US1114, Escondido
US1118, Glendale
US1123, Imperial
US1160 Renew Behavioral Health, Inc., Long Beach
US1368, Orange
US1370, Panorama City
US1351, Wildomar
US1133, Washington D.C.
US1217, Gainesville
US1229, Orange City
US1009, Atlanta
US1313, Marietta
US1311, Naperville
US1315, Naperville
US1103, Oak Brook
US1386, Wichita
US1261, Lake Charles
US1015, Baltimore
US1385 Ericksen Research And Development, Clinton
US1064, Creve Coeur
US1314, O'Fallon
US1266, Saint Charles
US1312, Berlin
US1222, Princeton
US1317, New York
US1171, Rochester
US1190, Staten Island
US1051, Cincinnati
US1054, Cleveland
US1334, Middleburg Heights
US1323, Oklahoma City
US1329, Oklahoma City
US1328, Austin
US1320, Plano
US1162, San Antonio
US1308, Orem
US1309, Richmond
BG1023, Targovishte
BG1025, Varna
CA1036 University of Calgary, Calgary
CA1038, Toronto
CO1003, Barranquilla
CO1001, Bello
CO1004, Bogotá
CO1002, Pereira
EE1007, Tallinn
EE1015, Viljandi
FR1041, Douai
FR1017, Élancourt
FR1009, Nantes
DE1078, Freiburg im Breisgau
DE1034, Mainz
DE1077, Mannheim
DE1081, Maulbronn
DE1076, Tübingen
HU1023, Budapest
HU1020, Gyula
IT1075, Cagliari
IT1073, Genova
IT1029, Messina
IT1068, Napoli
IT1074, Padua
IT1070, Pisa
IT1072 Osppedale Bambin gesu, Rome
LV1002, Jelgava
LV1008, Liepāja
LV1009, Riga
LV1007, Sigulda
MX1014, Culiacán
MX1011, Guadalajara
MX1013, Guadalajara
MX1022, Guadalajara
MX1023, Mazatlán
MX1003, Mexico City
MX1001, Nuevo León
PL1002, Bialystok
PL1050, Gdansk
PL1068, Kielce
PL1057, Lublin
PL1052, Poznan
PL1054, Wąbrzeźno
PL1051, Wroclaw
RU1009, Arkhangelsk
RU1059, Engel's
RU1046, Krasnodar
RU1011, Lipetsk
RU1004, Nizhny Novgorod
RU1010, Novosibirsk
RU1012, Rostov-on-Don
RU1044, Rostov-on-Don
RU1030, Saint Petersburg
RU1013, Saratov
RU1038, Saratov
RU1057, Tomsk
RU1048, Tonnel'nyy
RU1016, Yekaterinburg
RS1006 Clinic of Neurology and Psychiatry for Children and Adolescents, Belgrade
RS1010, Belgrade
RS1011, Kragujevac
RS1003, Niš
RS1007, Novi Sad
ZA1019, Cape Town
ZA1022, Randburg
ZA1023, Sandton
KR1035, Cheonan
UA1037, Gyeongsang
KR1032, Seoul
KR1038, Seoul
ES1041, Alcorcón
ES1044, Madrid
ES1043, Pamplona
ES1018 Hospital de Sabadell, Sabadell
ES1040, Torremolinos
UA1002, Kyiv
UA1019, Odesa
UA1001, Poltava
UA1004, Ternopil
GB1051, Glasgow
GB1047, Liverpool
Collaborators (1)
Takeda
INDUSTRY
H. Lundbeck A/S
INDUSTRY