Efficacy Study of Pembrolizumab With Entinostat to Treat Metastatic Melanoma of the Eye

PHASE2CompletedINTERVENTIONAL
Enrollment

29

Participants

Timeline

Start Date

February 21, 2018

Primary Completion Date

January 31, 2023

Study Completion Date

January 31, 2023

Conditions
Metastatic Uveal Melanoma
Interventions
DRUG

Pembrolizumab

200 mg administered intravenously (IV) every third week until progression or unacceptable toxicity for a maximum of 24 months

DRUG

Entinostat

5 mg by mouth (PO) once weekly until progression or unacceptable toxicity for a maximum of 24 months

Trial Locations (1)

SE-413 45

Department of oncology, Sahlgrenska University Hospital, Gothenburg

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Merck Sharp & Dohme LLC

INDUSTRY

collaborator

Syndax Pharmaceuticals

INDUSTRY

lead

Vastra Gotaland Region

OTHER_GOV

NCT02697630 - Efficacy Study of Pembrolizumab With Entinostat to Treat Metastatic Melanoma of the Eye | Biotech Hunter | Biotech Hunter