Intermittent G-CSF in Patients With Breast Cancer Receiving Adjuvant Docetaxel, Doxorubicin, and Cyclophosphamide (TAC)

PHASE2TerminatedINTERVENTIONAL
Enrollment

22

Participants

Timeline

Start Date

February 29, 2016

Primary Completion Date

December 31, 2017

Study Completion Date

December 31, 2017

Conditions
Breast CancerNeutropeniaFebrile Neutropenia
Interventions
DRUG

Filgrastim

Filgrastim (Gracinᵀᴹ) is administered at the D3, D5, D7, D9, and D11 of each cycle. A dose of 5 μg/kg/day filgrastim is administered S.C. either as a bolus injection or as a continuous injection. Administer into the outer upper arm, abdomen (except within 2 inches of navel), front middle thigh, or the upper outer buttocks area.

DRUG

Peg-filgrastim

Pegfilgrastim (Neulastaᵀᴹ) is administered at the D2 of each cycle. A dose of 6mg once a cycle is administered S.C., 24 (± 2) hours after completion of chemotherapy.

Trial Locations (1)

138-746

Asan Medical Center, Seoul

Sponsors
All Listed Sponsors
collaborator

Kyowa Kirin Co., Ltd.

INDUSTRY

lead

Asan Medical Center

OTHER