Study Evaluating Intepirdine (RVT-101) in Subjects With Dementia With Lewy Bodies: The HEADWAY-DLB Study

PHASE2CompletedINTERVENTIONAL
Enrollment

484

Participants

Timeline

Start Date

January 31, 2016

Primary Completion Date

December 31, 2017

Study Completion Date

December 31, 2017

Conditions
Dementia With Lewy Bodies
Interventions
DRUG

RVT-101 35 mg

once daily, oral, 35-mg tablets

DRUG

RVT-101 70 mg

once daily, oral, 35-mg tablets

DRUG

Placebo

once daily, oral, matching tablets

Trial Locations (65)

10032

US109, New York

16132

IT300, Genoa

19090

US120, Willow Grove

20007

US123, Washington D.C.

20133

IT301, Milan

22908

US101, Charlottesville

25123

IT306, Brescia

25125

IT302, Brescia

27514

US100, Chapel Hill

30331

US136, Atlanta

31052

FR952, Toulouse

32224

US111, Jacksonville

32806

US122, Orlando

33410

US137, Palm Beach Gardens

33431

US104, Boca Raton

33486

US116, Boca Raton

33609

US126, Tampa

40536

US105, Lexington

43210

US106, Columbus

44195

US110, Cleveland

44800

FR953, Saint-Herblain

46202

US118, Indianapolis

54500

FR955, Vandœuvre-lès-Nancy

55905

US102, Rochester

59037

FR957, Lille

60612

US112, Chicago

67000

FR950, Strasbourg

69100

FR951, Villeurbanne

69677

FR954, Bron

73039

IT304, Tricase

75010

FR959, Paris

75013

FR956, Paris

FR960, Paris

75390

US124, Dallas

80113

US141, Englewood

85006

US138, Phoenix

85013

US108, Phoenix

85351

US139, Sun City

85704

US125, Tucson

92270

US133, Rancho Mirage

92868

US119, Irvine

93030

US134, Oxnard

95816

US140, Sacramento

97210

US131, Portland

02459

US135, Newton

02196

US130, Quincy

M4N 3M5

CA200, Toronto

J1J 3H5

CA201, Sherbrooke

I-30126

IT305, Venice

1081 HV

NE402, Amsterdam

5223 GZ

NE401, 's-Hertogenbosch

3015 CE

NE400, Rotterdam

08028

SP600, Barcelona

08041

SP605, Barcelona

09006

SP602, Burgos

CB21 5EF

UK801, Cambridge

CM16 6TN

UK808, Epping

SO30 3JB

UK804, Southampton

BS10 5NB

UK807, Bristol

DD1 9SY

UK806, Dundee

TW76FY

UK805, Isleworth

SE5 8AF

UK800, London

W1G 9RU

UK809, London

M8 5RB

UK802, Manchester

NE4 5PL

UK803, Newcastle upon Tyne

Sponsors
All Listed Sponsors
lead

Axovant Sciences Ltd.

INDUSTRY