Dose Finding for the Treatment of Rhinitis/Rhinoconjunctivitis Against Mite Allergy

PHASE2UnknownINTERVENTIONAL
Enrollment

186

Participants

Timeline

Start Date

June 21, 2016

Primary Completion Date

July 31, 2020

Study Completion Date

July 31, 2020

Conditions
RhinitisRhinoconjunctivitis
Interventions
BIOLOGICAL

MM09 Mannosylated 5.000 subcutaneous

Mixture of the following mites: Dermatophagoides pteronyssinus and Dermatophagoides farinae, allergen extract with a concentration of 5.000 MTU (Mannosylated Therapeutic Units)/ml subcutaneous

BIOLOGICAL

MM09 Mannosylated 10.000 subcutaneous

Mixture of the following mites: Dermatophagoides pteronyssinus and Dermatophagoides farinae, allergen extract with a concentration of 10.000 MTU (Mannosylated Therapeutic Units)/ml subcutaneous

BIOLOGICAL

MM09 Mannosylated 30.000 subcutaneous

Mixture of the following mites: Dermatophagoides pteronyssinus and Dermatophagoides farinae, allergen extract with a concentration of 30.000 MTU (Mannosylated Therapeutic Units)/ml subcutaneous

BIOLOGICAL

MM09 Mannosylated 50.000 subcutaneous

Mixture of the following mites: Dermatophagoides pteronyssinus and Dermatophagoides farinae, allergen extract with a concentration of 50.000 MTU (Mannosylated Therapeutic Units)/ml subcutaneous

BIOLOGICAL

MM09 Mannosylated 5.000 sublingual

Mixture of the following mites: Dermatophagoides pteronyssinus and Dermatophagoides farinae, allergen extract with a concentration of 5.000 MTU (Mannosylated Therapeutic Units)/ml sublingual

BIOLOGICAL

MM09 Mannosylated 10.000 sublingual

Mixture of the following mites: Dermatophagoides pteronyssinus and Dermatophagoides farinae, allergen extract with a concentration of 10.000 MTU (Mannosylated Therapeutic Units)/ml sublingual

BIOLOGICAL

MM09 Mannosylated 30.000 sublingual

Mixture of the following mites: Dermatophagoides pteronyssinus and Dermatophagoides farinae, allergen extract with a concentration of 30.000 MTU (Mannosylated Therapeutic Units)/ml sublingual

BIOLOGICAL

MM09 Mannosylated 50.000 sublingual

Mixture of the following mites: Dermatophagoides pteronyssinus and Dermatophagoides farinae, allergen extract with a concentration of 50.000 MTU (Mannosylated Therapeutic Units)/ml sublingual

BIOLOGICAL

Subcutaneous placebo

Comparison between placebo and active group

BIOLOGICAL

Sublingual placebo

Comparison between placebo and active group

Trial Locations (14)

12004

Hospital Universitari de Castelló, Castellon

12540

Hospital de La Plana, Vila-real

46015

Hospital Arnau de Vilanova, Valencia

46017

Hospital Universitario Doctor Peset, Valencia

46026

HOSPITAL UNIVERSITARI I POLITÈCNIC LA FE Adults, Valencia

HOSPITAL UNIVERSITARI I POLITÈCNIC LA FE child, Valencia

46800

Hospital Lluis Alcanyis de Xátiva, Xátiva

46940

Hospital de Manises, Manises

03203

Hospital General Universitario de Elche, Elche

03293

Hospital Del Vinalopo, Elche

03600

Hospital General Universitario de Elda-Virgen de La Salud, Elda

03314

Hospital Vega Baja Orihuela, Orihuela

03010

Hospital General Universitario de Alicante, Alicante

03016

Hospital Vithas Internacional Medimar, Alicante

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Inmunotek S.L.

INDUSTRY

NCT02661854 - Dose Finding for the Treatment of Rhinitis/Rhinoconjunctivitis Against Mite Allergy | Biotech Hunter | Biotech Hunter