Impact of Anesthesia Maintenance Methods on Long-term Survival

NACompletedINTERVENTIONAL
Enrollment

1,228

Participants

Timeline

Start Date

April 1, 2015

Primary Completion Date

September 29, 2017

Study Completion Date

September 30, 2020

Conditions
AgedNeoplasmsSurgical Procedure, OperativeAnesthesia, InhalationAnesthesia, IntravenousSurvival
Interventions
DRUG

Sevoflurane

Sevoflurane will be administered by inhalation for anesthesia maintenance. The concentration of inhaled sevoflurane will be adjusted to maintain the BIS value between 40 and 60. Sevoflurane inhalational concentration will be decreased towards the end of surgery. Sevoflurane inhalation will be stopped at the end of surgery.

DRUG

Propofol

Propofol will be administered by intravenous infusion for anesthesia maintenance. The infusion rate of propofol will be adjusted to maintain the BIS value between 40 and 60. Propofol infusion rate will be decreased towards the end of surgery. Propofol infusion will be stopped at the end of surgery.

Trial Locations (17)

100034

Department of Anesthesiology and Critical Care Medicine, Peking University First Hospital, Beijing

Unknown

Beijing Shijitan Hospital, Beijing

Peking University Cancer Hospital, Beijing

University School and Hospital of Stomatology, Beijing

Cancer Hospital of Guangxi Medical University, Nanning

Shenzhen Second People's Hospital, Shenzhen

Guizhou Provincial People's Hospital, Guiyang

Hebei Medical University Forth Hospital, Shijiazhuang

The First Affiliated Hospital of Zhengzhou University, Zhenzhou

The Third Xiangya Hospital of Central South University, Changsha

Zhongda Hospital, Nanjing

Ningxia People's Hospital, Yinchuan

Affiliated Hospital of Qinghai University, Xining

Tang-Du Hospital, Xi'an

Shaanxi Provincial People's Hospital, Taiyuan

Shanxi Province Cancer Hospital, Taiyuan

Tianjin Nankai Hospital, Tianjin

All Listed Sponsors
collaborator

Hebei Medical University Fourth Hospital

OTHER

collaborator

The People's Hospital of Ningxia

OTHER

collaborator

Beijing Shijitan Hospital, Capital Medical University

OTHER

collaborator

Guizhou Provincial People's Hospital

OTHER

collaborator

Affiliated Hospital of Qinghai University

OTHER

collaborator

The Third Xiangya Hospital of Central South University

OTHER

collaborator

Cancer Hospital of Guangxi Medical University

OTHER

collaborator

Shanxi Provincial People's Hospital

OTHER_GOV

collaborator

Zhongda Hospital

OTHER

collaborator

The First Affiliated Hospital of Zhengzhou University

OTHER

collaborator

Tang-Du Hospital

OTHER

collaborator

Tianjin Nankai Hospital

OTHER

collaborator

Shenzhen Second People's Hospital

OTHER

lead

Peking University First Hospital

OTHER

NCT02660411 - Impact of Anesthesia Maintenance Methods on Long-term Survival | Biotech Hunter | Biotech Hunter