pRotective vEntilation With Veno-venouS Lung assisT in Respiratory Failure

PHASE3UnknownINTERVENTIONAL
Enrollment

1,120

Participants

Timeline

Start Date

May 12, 2016

Primary Completion Date

March 12, 2020

Study Completion Date

April 30, 2022

Conditions
Acute Respiratory Failure With Hypoxia
Interventions
DEVICE

VV-ECCO2R to enable lower tidal volume mechanical ventilation

In the intervention arm a dual lumen catheter will be inserted into a central vein. VV-ECCO2R is commenced and managed as per study manual. Tidal volumes are then reduced on mechanical ventilation to enable lower tidal volume ventilation. Lower tidal volume facilitated by VV-ECCO2R will continue for a least 2 days up to a maximum of 7 days

Trial Locations (1)

Unknown

Belfast Health and Social Care Trust, Belfast

Sponsors
All Listed Sponsors
collaborator

Queen's University, Belfast

OTHER

collaborator

Northern Ireland Clinical Trials Unit

OTHER

lead

Belfast Health and Social Care Trust

OTHER