Viral Inhibition in Children for Treatment of RSV

PHASE2CompletedINTERVENTIONAL
Enrollment

72

Participants

Timeline

Start Date

May 27, 2016

Primary Completion Date

March 31, 2019

Study Completion Date

April 9, 2019

Conditions
RESPIRATORY SYNCYTIAL VIRUS INFECTIONS
Interventions
DRUG

AK0529

AK0529 is a novel compound being developed for the treatment of RSV infection. The enteric coated drug pellets with sugar core can be administered orally with apple sauce/purée or yoghurt, or by flushing with 10% dextrose water via a nasogastric or other feeding tube, or upon a glucose wafer.

DRUG

Placebo

The placebo was made with the same smell and appearance as AK0529 but without the active ingredients. The placebo supplements are composed primarily of microcrystaline cellulose pellet.

Trial Locations (28)

4101

Lady Cilento Children's Hospital, South Brisbane

Unknown

Gold Coast University Hospital, Gold Coast

Women's and Children's Hospital, Adelaide

Prince of Wales Hospital, Shatin

Soroka University Medical Center, Beersheba

Ruth Rappaport Children's Hospital, Haifa

Schneider Children's Medical Center, Petach Tikvah

American University of Beirut Medical Center, Beirut

Makassed General Hospital, Beirut

Rafik Hariri University Hospital, Beirut

Saint George Hospital University Medical Center, Beirut

Hospital Tuanku Jaafar, Seremban

Hospital Sibu, Sibu

Hospital Selayang, Batu Caves

Hospital Tengku Ampuan Rahimah, Klang

University Malaya Medical Center, Kuala Lumpur

Specjalistyczny Zespół Opieki Zdrowotnej nad Matką i Dzieckiem w Poznaniu, Poznan

Nowy Szpital w Świeciu, Gmina Świecie

Szpital im. Świętej Jadwigi Śląskiej w Trzebnicy, Trzebnica

Kaohsiung Chang Gung Memorial Hospital, Kaohsiung City

Mackay Memorial Hospital, Taipei

National Taiwan University Hospital, Taipei

Taipei Municipal Wanfang Hospital, Taipei

Linkou Chang Gung Memorial Hospital, Taoyuan District

Cukurova University Balcali Hospital, Adana

Eskisehir Osmangazi University Faculty of Medicine, Eskişehir

Ege University Medical Faculty, Izmir

Marmara University Faculty of Medicine, Istanbul

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Ark Biosciences Pty Ltd.

UNKNOWN

lead

Shanghai Ark Biopharmaceutical Co., Ltd.

INDUSTRY

NCT02654171 - Viral Inhibition in Children for Treatment of RSV | Biotech Hunter | Biotech Hunter