A Phase 2 Study to Assess the Safety and Efficacy of IMO-2125 With 8 mg Ipilimumab in Patients With Metastatic Melanoma

PHASE2CompletedINTERVENTIONAL
Enrollment

53

Participants

Timeline

Start Date

December 31, 2015

Primary Completion Date

February 29, 2020

Study Completion Date

May 31, 2021

Conditions
Metastatic Melanoma
Interventions
DRUG

IMO-2125

Drug: IMO-2125 Intratumoral injection administered as 9 doses on Weeks 1, 2, 3, 5, 8, 11, 17, 23, and 29.

DRUG

Ipilimumab

4 doses administered intravenously at a dose of 3 mg/kg over 90 minutes on Weeks 2, 5, 8, and 11.

Trial Locations (10)

10029

Icahn School Of Medicine at Mount Sinai, New York

14263

Roswell Park Cancer Institute, Buffalo

33612

Moffitt Cancer Center Research Institute, Tampa

37232

Vanderbilt-Ingram Cancer Center, Nashville

44718

Gabrail Cancer Center, Canton

52242

University of Iowa Hospitals and Clinics, Iowa City

66205

University of Kansas Cancer Center, Westwood

77030

MD Anderson Cancer Center, Houston

84112

University of Utah- Huntsman Cancer Institute, Salt Lake City

85719

The University of Arizona Cancer Center, Tucson

Sponsors
All Listed Sponsors
lead

Idera Pharmaceuticals, Inc.

INDUSTRY

NCT02644967 - A Phase 2 Study to Assess the Safety and Efficacy of IMO-2125 With 8 mg Ipilimumab in Patients With Metastatic Melanoma | Biotech Hunter | Biotech Hunter