A Study of Duvelisib and Venetoclax in Subjects With Relapsed or Refractory Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, or Indolent or Aggressive Non-Hodgkin Lymphoma, Who Have Not Previously Received a Bcl-2 or PI3K Inhibitor

PHASE1WithdrawnINTERVENTIONAL
0
Timeline

Start Date

July 31, 2016

Primary Completion Date

January 31, 2020

Study Completion Date

February 28, 2021

Conditions
Chronic Lymphocytic LeukemiaSmall Lymphocytic LymphomaNon-Hodgkin Lymphoma
Interventions
DRUG

Duvelisib

Duvelisib will be taken continuously. This is a defining dose study, therefore the dose of Duvelisib may change.

DRUG

Venetoclax

Venetoclax will be taken continuously. This is a defining dose study, therefore the dose of Venetoclax will change.

Trial Locations (10)

21287

Site Reference ID/Investigator# 145674, Baltimore

29605

Site Reference ID/Investigator# 148559, Greenville

46526

Site Reference ID/Investigator# 148561, Goshen

48202

Site Reference ID/Investigator# 148010, Detroit

60426

Site Reference ID/Investigator# 148562, Harvey

60611

Site Reference ID/Investigator# 147922, Chicago

63110

Site Reference ID/Investigator# 147747, St Louis

85724-5024

Site Reference ID/Investigator# 145677, Tucson

02215

Site Reference ID/Investigator# 145145, Boston

03756

Site Reference ID/Investigator# 145146, Lebanon

Sponsors

Lead Sponsor

All Listed Sponsors
collaborator

Infinity Pharmaceuticals, Inc.

INDUSTRY

lead

AbbVie

INDUSTRY