Effects of Adjunct Photodynamic Therapy in the Treatment of Type 2 Diabetic Patients With Chronic Periodontitis

NACompletedINTERVENTIONAL
Enrollment

20

Participants

Timeline

Start Date

April 30, 2014

Primary Completion Date

March 31, 2015

Study Completion Date

October 31, 2015

Conditions
Chronic PeriodontitisDiabetes Mellitus
Interventions
PROCEDURE

Ultrasonic debridement

All periodontal pockets received ultrasonic debridement (Cavitron, Dentsply) with specific inserts (UI25KSF10S, Hu-Friedy). All diseased sites were instrumented in one session by an experienced periodontist.

PROCEDURE

Antimicrobial photodynamic therapy

After ultrasonic debridement, one randomly selected periodontal pocket received an additional aPDT performed by a trained operator (NMRBA). One pocket with probing depth ≥ 5mm in each patient was randomly selected to aPDT. After washing the pocket with saline solution, the photosensitizer (methylene blue 10mg/ml) was applied to the bottom of the pocket in a coronal direction. Following this, the pocket was exposed to a diode laser light with a fibre optic application for 1 min (Thera Lase DMC - Brazil), with wavelength of 660nm, power of 60mW and fluency of 129J/cm2.

Trial Locations (1)

12245-000

Instituto de Ciência e Tecnologia de São José dos Campos - UNESP, Sâo José Dos Campos

All Listed Sponsors
lead

Universidade Estadual Paulista Júlio de Mesquita Filho

OTHER

NCT02627534 - Effects of Adjunct Photodynamic Therapy in the Treatment of Type 2 Diabetic Patients With Chronic Periodontitis | Biotech Hunter | Biotech Hunter