Dose Finding Study of Contraceptive Vaginal Ring With Different Estradiol Levels in Combination With Nestorone

PHASE2CompletedINTERVENTIONAL
Enrollment

65

Participants

Timeline

Start Date

January 31, 2016

Primary Completion Date

March 31, 2017

Study Completion Date

March 31, 2017

Conditions
Suppression of Ovulation
Interventions
DEVICE

Nestorone®/Estradiol Contraceptive Vaginal Ring

Three arms of contraceptive vaginal rings contain a fixed dose (200 mcg/day) of Nestorone® and escalating doses (75 µg/d, 100 µg/d, or 200 µg/d /day) of estradiol

Trial Locations (7)

10032

Columbia University, New York

19104

University of Pennsylvania, Philadelphia

23507

Eastern Virginia Medical School (EVMS), Norfolk

45267

University of Cincinnati, Cincinnati

84106

University of Utah, Salt Lake City

95817

University of California, Davis, Sacramento

97239

Oregon Health & Science Unit, Portland

Sponsors

Lead Sponsor

All Listed Sponsors
collaborator

Population Council

OTHER

collaborator

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

NIH

lead

Premier Research

OTHER