Randomised Study of Interferon-free Treatment for Recently Acquired Hepatitis C in PWID and People With HIV Coinfection.

PHASE3CompletedINTERVENTIONAL
Enrollment

222

Participants

Timeline

Start Date

March 9, 2017

Primary Completion Date

March 23, 2020

Study Completion Date

March 23, 2020

Conditions
Hepatitis C
Interventions
DRUG

SOF/VEL for 6 weeks

Open-label SOF/VEL 400mg/100mg once daily to be given to participants randomised to Arm A (6 weeks short treatment duration).

DRUG

SOF/VEL for 12 weeks

Open-label SOF/VEL 400mg/100mg once daily to be given to participants randomised to Arm B (12 weeks standard treatment duration).

Trial Locations (25)

1142

Auckland City Hospital, Auckland

1340

Kirketon Road Centre, Sydney

2010

St. Vincent's Hospital, Sydney

2052

The Kirby Institute, University of New South Wales Australia, Sydney

3004

The Alfred Hospital, Melbourne

3010

Bern University Hospital, Bern

3050

Royal Melbourne Hospital, Melbourne

5000

Royal Adelaide Hospital, Adelaide

6900

Fondazione Epatocentro Ticino, Lugano

8091

University Hospital Zurich, Zurich

10243

Praxis Dr Cordes, Berlin

10439

Zentrum für Infektiologie Berlin-Prenzlauer Berg, Berlin

21287

Johns Hopkins University, Baltimore

53105

University Hospital of Bonn, Bonn

60596

Infektio-Research GmbH, Frankfurt

02114-2621

Massachusetts General Hospital, Boston

V6Z 1Y6

St Paul's Hospital, Vancouver

V8W 1M8

Cool Aid Community Health Centre, Victoria

ON M57 2S8

Toronto General Hospital, Toronto

QC H2X 1P1

Centre Hospitalier de l' Universite de Montreal, Montreal

1105 AZ

Academic Medical Centre, University of Amsterdam, Amsterdam

BN2 1ES

Brighton & Sussex University Hospitals NHS Trust, Brighton

M8 5RB

Pennine Acute Hospitals NHS Trust, Manchester

NW3 2QG

Royal Free Hospital, London

SW10 9NH

Chelsea & Westminster Hospital, London

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Kirby Institute

OTHER_GOV

NCT02625909 - Randomised Study of Interferon-free Treatment for Recently Acquired Hepatitis C in PWID and People With HIV Coinfection. | Biotech Hunter | Biotech Hunter