tDCS Intervention in Primary Progressive Aphasia

NACompletedINTERVENTIONAL
Enrollment

61

Participants

Timeline

Start Date

April 30, 2013

Primary Completion Date

July 12, 2023

Study Completion Date

August 11, 2023

Conditions
Primary Progressive AphasiaMCIFTD
Interventions
DEVICE

Active HD-tDCS plus Speech-Language Therapy

Stimulation will be delivered by a battery-driven constant current stimulator. The electrical current will be administered to a pre-specified region of the brain (inferior frontal gyrus). The stimulation will be delivered at an intensity of 2mA (estimated current density 0.04 mA/cm2; estimated total charge 0.048C/cm2) in a ramp-like fashion for a maximum of 20 minutes. Speech-language therapy will be oral and written naming.

DEVICE

Sham plus Speech-Language Therapy

Speech-language therapy will be administered during sham stimulation. Current will be administered in a ramp-line fashion but after the ramping the intensity will drop to 0 mA. Speech-language therapy will be oral and written naming.

Trial Locations (1)

21204

Johns Hopkins Hospital, Baltimore

All Listed Sponsors
collaborator

National Institutes of Health (NIH)

NIH

collaborator

National Institute on Deafness and Other Communication Disorders (NIDCD)

NIH

lead

Johns Hopkins University

OTHER

NCT02606422 - tDCS Intervention in Primary Progressive Aphasia | Biotech Hunter | Biotech Hunter