Testing TH-302, in Combination With Preoperative Chemoradiotherapy, in Esophageal Cancer.

PHASE1WithdrawnINTERVENTIONAL
0
Timeline

Start Date

December 31, 2015

Primary Completion Date

April 30, 2016

Study Completion Date

April 30, 2016

Conditions
Esophageal Cancer
Interventions
DRUG

TH-302

TH-302 day 4 (pre-treatment) and weekly during chemo-radiotherapy (CRT)

OTHER

HX4 scan

HX 4 scan day 1 and day 8

DRUG

Carboplatin

2mg/ml/min

DRUG

Paclitaxel

50 mg/m2

RADIATION

Radiotherapy

23 x 1.8 Gy

PROCEDURE

surgery

minimally invasive transhiatal approach including a one-field node dissection or transthoracic approach with a two-field lymph node dissection

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Threshold Pharmaceuticals

INDUSTRY

collaborator

Zuyderland Medical Centre

OTHER

lead

Maastricht Radiation Oncology

OTHER

NCT02598687 - Testing TH-302, in Combination With Preoperative Chemoradiotherapy, in Esophageal Cancer. | Biotech Hunter | Biotech Hunter