60
Participants
Start Date
April 30, 2016
Primary Completion Date
October 31, 2039
Study Completion Date
October 31, 2040
Proton Radiation
Proton Radiation 40.50 Gy relative biological effectiveness (RBE) in 18 fractions to gross disease and elective nodal volume followed by a 22.50 Gy (RBE) in 10 fraction boost to gross disease. Total dose 63 Gy (RBE) in 28 fractions over 6 weeks.
Capecitabine
Concomitant oral chemotherapy, capecitabine 1000mg by mouth twice daily, 5 days a week (M-F) on radiation days only.
Surgical resection
Surgery between 8 and 16 weeks of radiotherapy completion if radiographic studies suggest operability.
RECRUITING
Inova Schar Cancer Institute, Fairfax
ACTIVE_NOT_RECRUITING
University of Florida Proton Therapy Institute, Jacksonville
RECRUITING
McLaren Proton Therapy Center, Flint
RECRUITING
Northwestern Medicine Chicago Proton Center, Warrenville
University of Florida Health
OTHER
Proton Collaborative Group
NETWORK