Enhanced Provision of Male Circumcision (MC) for HIV Prevention, Rakai, Uganda

PHASE2/PHASE3CompletedINTERVENTIONAL
Enrollment

501

Participants

Timeline

Start Date

October 31, 2014

Primary Completion Date

July 31, 2015

Study Completion Date

July 31, 2015

Conditions
Neonatal Male Circumcision
Interventions
PROCEDURE

Neonatal circumcision under topical anesthesia

"The standard procedure for neonatal circumcision is as follows: combined analgesia was topical 2.5% lidocaine and 2.5% prilocaine \<1 gm applied 60 minutes and 40mg acetaminophen suppository 30 minutes prior to surgery. Infants were given a 24% sucrose solution pacifier if needed. Infants under 2 weeks of age received subcutaneous Vitamin K 1 mg. The perineum cleaned, and the penis swabbed with povidone iodine. Hemostats were applied at 3 and 9 o'clock positions and the glans pushed down. Traction was applied before placing the Mogen clamp, the clamp was closed for 5 minutes and the foreskin removed with a scalpel.~Petroleum jelly (e.g., Vaseline) was applied to the glans and the wound covered with sterile gauze. Infants were observed for one hour. Mothers were instructed in wound care."

All Listed Sponsors
collaborator

Rakai Health Sciences Program

OTHER

collaborator

MRC/UVRI and LSHTM Uganda Research Unit

OTHER

lead

Johns Hopkins Bloomberg School of Public Health

OTHER

NCT02596282 - Enhanced Provision of Male Circumcision (MC) for HIV Prevention, Rakai, Uganda | Biotech Hunter | Biotech Hunter