Study to Evaluate the Clinical Efficacy and Safety of Subcutaneously Administered C1 Esterase Inhibitor for the Prevention of Angioedema Attacks in Adolescents and Adults With Hereditary Angioedema

PHASE3CompletedINTERVENTIONAL
Enrollment

75

Participants

Timeline

Start Date

November 1, 2015

Primary Completion Date

July 24, 2017

Study Completion Date

July 24, 2017

Conditions
Hereditary Angioedema (HAE)
Interventions
DRUG

C1 esterase inhibitor [human] liquid

C1 Esterase Inhibitor \[Human\] Liquid administered Subcutaneously as specified on specified days

DRUG

Placebo

Placebo

Trial Locations (27)

1125

Semmelweis Egyetem, Budapest

8035

Hospital Universitario Vall d'Hebron, Barcelona

20815

Institute For Asthma and Allergy, Chevy Chase

28046

Hospital Universitario La Paz, Madrid

28277

Clinical Research of Charlotte, Charlotte

30060

Atlanta Allergy and Asthma Clinic, Marietta

41013

Hospital Universitario Virgen del Rocio, Seville

44130

Clinical Research Solutions, Middleburg Heights

45231

Bernstein Clinical Research Center Inc, Cincinnati

46026

Hospital Universitari i Politecnic La Fe de Valencia, Valencia

52621

Chaim Sheba Medical Center, Ramat Gan

63141

Washington University, St Louis

64239

Tel Aviv Sourasky Medical Center, Tel Aviv

64546

Hämophilie Zentrum Rhein Main GmbH, Mörfelden-Walldorf

74133

Allergy Clinic of Tulsa, Tulsa

75231

AARA Research Center, Dallas

80112

IMMUNOe Research Centers, Centennial

80907

Asthma and Allergy Associates PC, Colorado Springs

85251

Medical Research of Arizona, Scottsdale

90404

AIRE Medical of Los Angeles, Santa Monica

94598

Bay Area Allergy, Walnut Creek

99202

Premier Clinical Research, Spokane

540072

MediQuest Clinical Research Center, Târgu Mureş

07410

Allergy Asthma and Immunology, Fair Lawn

08830

Allergy Treatment Center of New Jersey, Iselin

L8N 325

McMaster University Medical Center, Hamilton

K1Y 4G2

Ottawa Allergy Research Corporation, Ottawa

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Shire

INDUSTRY