"Managing Neovascular (Known as Wet) Age-related Macular Degeneration Over 2 Years Using Different Treatment Schedules of 2 mg Intravitreal Aflibercept Injected in the Eye"

PHASE4CompletedINTERVENTIONAL
Enrollment

287

Participants

Timeline

Start Date

November 19, 2015

Primary Completion Date

April 26, 2019

Study Completion Date

April 26, 2019

Conditions
Macular Degeneration
Interventions
DRUG

Eylea (Intravitreal Aflibercept, VEGF Trap-Eye, BAY86-5321)

3 monthly doses followed by individualized treatment intervals of between 8 to16 weeks based on protocol-defined anatomical criteria

DRUG

Eylea (Intravitreal Aflibercept, VEGF Trap-Eye, BAY86-5321)

3 monthly doses followed by five 8-weekly doses (5 x 2Q8), then by individualized treatment intervals of between 8 to 16 weeks based on protocol-defined anatomical criteria

Trial Locations (39)

1062

Budapest

1085

Budapest

1106

Budapest

1115

Budapest

1125

Budapest

1133

Budapest

2000

Sydney

2135

Strathfield

2145

Westmead

3002

East Melbourne

4032

Debrecen

7249

Launceston

7621

Pécs

9700

Szombathely

10713

Berlin

20132

Milan

20157

Milan

30625

Hanover

33012

Oviedo

35128

Padua

50009

Zaragoza

50924

Cologne

53105

Bonn

66280

Sulzbach

72076

Tübingen

79106

Freiburg im Breisgau

94010

Créteil

L8G 5E4

Hamilton

K2B7E9

Ottawa

J7H1S6

Boisbriand

06006

Nice

09116

Chemnitz

00198

Rome

Unknown

Madrid

CT1 3NG

Canterbury

BS12LX

Bristol

L7 8XP

Liverpool

EC1V2PD

London

OX3 9DU

Oxford

Sponsors

Lead Sponsor

All Listed Sponsors
collaborator

Regeneron Pharmaceuticals

INDUSTRY

lead

Bayer

INDUSTRY